Daniela Piazza was born in Caserta, Italy, to an Italian father and a Danish mother. For over two decades, she built a career as an actress, director, and screenwriter across Italian and international film, theatre, and television before turning to visual art.

Her first encounters with visual and installation art took place in Rome in 2007. She conceived the narrative for Life Box Live, a project by artist Adalgisa Romano presented as part of the exhibition IN/S in Rome, curated by Daniele Sterpetti at Duncan 3.0 Spazio Per-formativo Arti Contemporanee, in which she also performed alongside Elodie Treccani. That same year, she appeared as one of ten living “body-objects” in Last Ciak 05 [The Eternal Beauty], a live performance by the collective Corpicrudi (Samantha Stella and Sergio Frazzingaro).

She has worked as an actress in film, theater, and television since the 1990s. Among her most notable performances is a leading role in Gabriele Muccino’s "Baciami Ancora". She also appeared in "La Ragazza nella Nebbia", the directorial debut of writer Donato Carrisi. She has worked on various international productions, including the PBS film "The House of Mirth" (directed by Michael Epstein), in which she played Lily Bart, and the TNT production of "Julius Caesar" (directed by Uli Edel), in which she played Cornelia.

In 2008, she made her debut as a director with the short film Cose che succedono, which she also wrote, winning the Silver Remi Award for Independent Short Subjects at the Houston International Film Festival.

Since 2017, she has worked as a visual artist under the pseudonym D, developing a personal practice across collage, photography, video, and poetry, centered on the themes of childhood and femininity. In 2025, she began a parallel collaborative practice with Rachele Palladino as the duo DUAE (the feminine plural of the Latin numeral duo).